Plants with Anti-Diabetes Mellitus Properties

Plants with Anti-Diabetes Mellitus Properties

Author: Appian Subramoniam

Publisher: CRC Press

ISBN: 0367574969

Category: Diabetes

Page: 591

View: 418

The incidence and severity of diabetes mellitus is increasing worldwide, presenting a significant burden to society both in economic terms and overall well-being. Fortunately, time-tested anti-diabetes mellitus plant foods exist that are safe and could be effective in addressing this condition when consumed judiciously with a concomitant change in lifestyle. Plants with Anti-Diabetes Mellitus Properties presents an exhaustive compilation of the anti-diabetes mellitus activities of more than 1000 plants occurring worldwide. The author provides a brief botanical description, distribution, pharmacological properties, and phytochemicals, where appropriate. A list of traditional medicinal plants used to treat diabetes, but not tested for anti-diabetic activity, is also given. This unique reference highlights anti-diabetes mellitus plant foods along with a list of the edible parts of plants with anti-diabetes mellitus properties. Anti-diabetes mellitus nutraceuticals are described with guidelines for the development of food supplements and formulations of diets appropriate for diabetic patients. This is a valuable source of information for researchers, students, doctors, diabetic patients, and other individuals wanting to learn more about plant-based treatments for diabetes mellitus.

Antidiabetic Potential of Plants in the Era of Omics

Antidiabetic Potential of Plants in the Era of Omics

Author: Deepu Pandita

Publisher: CRC Press

ISBN: 9781000574999

Category: Medical

Page: 443

View: 761

Here is an informative overview of diabetes mellitus in conjunction with plant-based treatments. It discusses available methods for studying the antidiabetic activities of scientifically developed plant products, mechanisms of action, their therapeutic superiority, and current genome editing research perspectives and biotechnological approaches. The book begins with an introduction to diabetes, giving a brief overview of the history, diagnosis, classification, pathophysiology, and risk factors. It goes on to review traditional uses of plants for diabetes along with ethnobotanical information. The results of scientific studies on the various modes of action of antidiabetic plants are discussed, such as the molecular aspects of active plantbased antidiabetic drug molecules. A section featuring recent biotechnological advancements of antidiabetic plants and plant-based antidiabetic drugs covers advances in molecular breeding and application of molecular markers, biotechnologically engineered transgenic medicinal plants, and advances in genomic editing tools and techniques.

Plants with Anti-Diabetes Mellitus Properties

Plants with Anti-Diabetes Mellitus Properties

Author: Appian Subramoniam

Publisher: CRC Press

ISBN: 9781482249903

Category: Health & Fitness

Page: 591

View: 345

The incidence and severity of diabetes mellitus is increasing worldwide, presenting a significant burden to society both in economic terms and overall well-being. Fortunately, time-tested anti-diabetes mellitus plant foods exist that are safe and could be effective in addressing this condition when consumed judiciously with a concomitant change in lifestyle. Plants with Anti-Diabetes Mellitus Properties presents an exhaustive compilation of the anti-diabetes mellitus activities of more than 1000 plants occurring worldwide. The author provides a brief botanical description, distribution, pharmacological properties, and phytochemicals, where appropriate. A list of traditional medicinal plants used to treat diabetes, but not tested for anti-diabetic activity, is also given. This unique reference highlights anti-diabetes mellitus plant foods along with a list of the edible parts of plants with anti-diabetes mellitus properties. Anti-diabetes mellitus nutraceuticals are described with guidelines for the development of food supplements and formulations of diets appropriate for diabetic patients. This is a valuable source of information for researchers, students, doctors, diabetic patients, and other individuals wanting to learn more about plant-based treatments for diabetes mellitus.

Anti-Diabetes Mellitus Plants

Anti-Diabetes Mellitus Plants

Author: Appian Subramoniam

Publisher: CRC Press

ISBN: 149875323X

Category: Diabetes

Page: 390

View: 552

The incidence and severity of diabetes mellitus is increasing worldwide, presenting a significant burden to society both in economic terms and overall well-being. There is a growing demand for novel safe and effective medicines due to the limited efficacy and undesirable side effects of current conventional drugs. We now have a great opportunity to develop plant-based therapies for diabetes mellitus with superior efficacy and safety utilizing modern science and technology. Anti-Diabetes Mellitus Plants: Active Principles, Mechanisms of Action and Sustainable Utilization begins with a detailed introduction to diabetes mellitus including current treatments for this disease in conventional medicine. It provides an authoritative overview of available methods for studying the anti-diabetes mellitus activities of plant products. The book highlights the likely therapeutic superiority of scientifically developed combinations of anti-diabetes mellitus phytochemicals and polyherbal formulations. This unique reference covers the development of polyherbal formulations and conventional combination drugs with desired targets of action for diabetes mellitus patients. In this book, more than 300 anti-diabetes phytochemical compounds are extensively covered and updated with their pharmacological properties. It will serve as a valuable source of information for researchers, students, doctors, biotechnologists, diabetic patients, and other individuals wanting to learn more about plant-based treatments for diabetes mellitus.

Biotechnology of Anti-diabetic Medicinal Plants

Biotechnology of Anti-diabetic Medicinal Plants

Author: Saikat Gantait

Publisher: Springer Nature

ISBN: 9789811635298

Category: Medical

Page: 482

View: 681

This book is a unique overview of insights on the genetic basis of anti-diabetic activity, chemistry, physiology, biotechnology, mode-of-action, as well as cellular mechanisms of anti-diabetic secondary metabolites from medicinal plants. The World Health Organization estimated that 80% of the populations of developing countries rely on traditional medicines, mostly plant drugs, for their primary health care needs. There is an increasing demand for medicinal plants having anti-diabetic potential in both developing and developed countries. The expanding trade in medicinal plants has serious implications on the survival of several plant species, with many under threat to become extinct. This book describes various approaches to conserve these genetic resources. It discusses the whole spectrum of biotechnological tools from micro-propagation for large-scale multiplication, cell-culture techniques to the biosynthesis and enhancement of pharmaceutical compounds in the plants. It also discusses the genetic transformation as well as short- to long-term conservation of plant genetic resources via synthetic seed production and cryopreservation, respectively. The book is enriched with expert contributions from across the globe. This reference book is useful for researchers in the pharmaceutical and biotechnological industries, medicinal chemists, biochemists, botanists, molecular biologists, academicians, students as well as diabetic patients, traditional medicine practitioners, scientists in medicinal and aromatic plants, Ayurveda, Siddha, Unani and other traditional medical practitioners.

Phytochemical and anti-diabetic activities of different plant part extracts among black pepper (Piper nigrum) varieties in comparison with Piper longum and Piper betel

Phytochemical and anti-diabetic activities of different plant part extracts among black pepper (Piper nigrum) varieties in comparison with Piper longum and Piper betel

Author: Prem Jose Vazhacharickal

Publisher: GRIN Verlag

ISBN: 9783668476233

Category: Science

Page: 79

View: 398

Scientific Study from the year 2017 in the subject Chemistry - Bio-chemistry, grade: 1.5, Mar Augusthinose College, course: Biotechnology, language: English, abstract: Diabetes mellitus is a clinical metabolic syndrome, which has been resulted from the malfunction or insufficiency of insulin production. Diabetes is the major threat to the people in developing and developed country. Prolonged diabetic condition can affect organs and synthetic drug if consumed by the patient can cause side-effects and impaired immune system. The synthetic medicine used for the treatment of diabetes is usually costlier, create side-effects and do not ensure complete recovery from the disorder but on the other hand, medicinal plants create a great impact in the human immune system. The medicinal plant produces a variety of chemical substances which shows significant therapeutic properties. This study highlights the potential anti-diabetic significance and phytochemical activity of different varieties Piper nigrum (Black pepper) and different strategies used for the assessment of these activities. The piperaceae family consist of 12 genera and more than 1400 species and is one of the largest families and widely distributed across the tropical and sub-tropical regions and over the high ranges of Andes and Sub Himalayas. Piper species naturally have multi-dimensional affect on various parts of the body often mentioned as antipyretic, diuretic, aphrodisiac, immune- stimulant and antioxidant, hepatoprotective, digestive, antiseptic and anti-diabetic. Phytochemical analysis of Methanol and Petroleum -ether extracts was carried out and different plant parts were collected from different districts across Kerala. Phytochemical which is identified from Piper nigrum present an exciting opportunity for the development of new type of therapeutics for diabetes mellitus. Some anti-diabetic plants exert their action by stimulating the function or number of beta cells and thus increasing insulin production with least side effects. Further investigations are required and more attention should be drawn to explore the biological activity of hundreds of traditionally used plants. Both in-vivo and in-vitro assessment is necessary for the assessment of anti-diabetic properties from the natural resources.

Medicinal Plants for the Treatment of Metabolic Disorders. Part 3

Medicinal Plants for the Treatment of Metabolic Disorders. Part 3

Author: Anaberta Cardador Martínez

Publisher:

ISBN: 1536180645

Category:

Page:

View: 710

This book provides a complete review of multiple metabolic disorders and the use of phytochemicals for their prevention and treatment. When describing each metabolic disorder, all authors describe the main health alterations, providing the most current figures and statistics worldwide; medicinal plants used in traditional medicine for its treatment and scientific information related to their potential to prevent or treat each condition. Authors also include a complete scientific background check, comprehensive analysis of all phytochemicals recommended for each disorder, a description of the mechanism(s) of action and in vivo and/or in vitro studies. Within this volume, a series of 7 plant species, recommended to treat or prevent the previously described disorders, are presented with their botanical information, traditional use in different cultures and countries, and the available scientific information validating their health benefits. Besides, six main metabolic disorders are described, providing a full scientific background for its general understanding, and three study cases are presented, where metabolic disorders are analyzed and approached from different medical and pharmaceutical angles.Chapter 1 - Soybean contains a great nutritional value, which makes it an excellent food for the human diet. It has large amounts of protein and lipids and also provides fiber, calcium, iron, zinc, and several vitamins. For these reasons, the possible benefits of soy consumption for human health have been studied. Although the results obtained to date have not been conclusive, thanks to its high content of isoflavones (phytochemicals with estrogenic activity), soy is attributed with anti-inflammatory, antioxidants and antifungals properties. Moreover, soybeans could provide significant benefits to patients with cardiovascular diseases, cancer, or diabetes.Chapter 2 - Oil, proteins, vitamins, fibers, and phytochemicals present in the avocado plant have shown the excellent capability of not only addressing the prevalence of these metabolic diseases but also being safe and having minimal side effects. The general objective of this book chapter is to review the bioactive compounds and their action to promote health benefits in the prevention and management of metabolic disorders.Chapter 3 - Heliopsis longipes roots, which contain affinin, has been used in traditional cuisine as a spice for its pungent. Due to its tingling and numbing properties, it is frequently applied to heal diverse pains such as toothache, earache, and headache. Within this chapter, its applications on anti-inflammatory activity, local anesthetic, analgesic, anti-mutagenic, and antioxidant activity, will be reviewed.Chapter 4 - The species Opuntia ficus-indica (L.) Mill., represents a good source of nutrients and antioxidants in the diet of consumers. This chapter aims to offer a simple and economical alternative formulation of artisan conserves prepared with nopal, in which the antioxidant activity was evaluated.Chapter 5 - Metabolic syndrome is known as a group of metabolic abnormalities that increase the risk of developing cardiovascular diseases and type 2 diabetes. The cost of health for companies is very high for workers who have obesity or metabolic syndrome compared to healthy workers. Metabolic syndrome is closely related to obesity, and this, in turn, is associated with a poor diet (high intake of carbohydrates and fats). This chapter explains the decrement of risk factors in workers of Young Living Ecuador Farm based on the Health Belief Model. Chapter 6 - The objective of this chapter book was to analyze the evidence obtained by clinical studies reported by scientific literature. Clinical studies have employed different components or products of grapes, such as pulp, freeze-dried grape, extracts, wine, and a distinct dose of resveratrol, to demonstrate their biological properties against diabetes mellitus, hypertension, and obesity.Chapter 7 - The main purpose of this chapter is to describe the analysis of whether glycated hemoglobin values could be used as a limit marker for earlier diagnosis of type 2 DM in overweight patients. This was a nonexperimental, analytical, retrospective, longitudinal study of 100 overweight patients diagnosed with type 2 DM. The study was carried out in 2014 at Teodoro Maldonado Carbo Hospital, Guayaquil, Ecuador.Chapter 8 - Rosemary is classified not only as spice or ornamental but also as a medicinal plant. It is an important source of volatile and non-volatile compounds. The proportion of them varies in function of diverse factors as a region of growth, environment, extraction treatment, and others. Thanks to its composition, rosemary owners several properties such as anti-obesity, anti-diabetes, anti-cancer, among others, thus the importance of this plant over metabolic diseases is presented in this chapter.Chapter 9 - Agave has been used in traditional medicine as an anesthetic, anticonvulsant, antipyretic, urinary antiseptic, cathartic, cicatricial, and regenerative, diuretic, emmenagogue, and eupeptic. Agave extracts and derived agave products have been used to prevent several metabolic diseases, such as diabetes and cancer. However, more studies are needed to support these effects.

Bioactive Compounds of Medicinal Plants

Bioactive Compounds of Medicinal Plants

Author: Megh R. Goyal

Publisher: CRC Press

ISBN: 9781351376419

Category: Science

Page: 344

View: 883

This volume sheds new light on the immense potential of medicinal plants for human health from different technological aspects. It presents new research on bioactive compounds in medicinal plants that provide health benefits, including those that have proven especially effective in treating and managing diabetes mellitus and hypertension. It looks at the medicinal properties, antioxidant capacity, and antimicrobial activity of plants and provides scientific evidence on the use of medicinal plants in the treatment of certain diseases. Many of the plants described in the chapters are easily accessible and are believed to be effective with fewer side effects in comparison to modern drugs in the treatment of different diseases.

How to Treat Diabetes Using Soursop Leaves

How to Treat Diabetes Using Soursop Leaves

Author: Dr Adel Tundey

Publisher: Independently Published

ISBN: 9798653597367

Category:

Page: 30

View: 737

Diabetes mellitus is a chronic endocrine disorder of carbohydrate, fat and protein metabolism characterized by an increase in both fasting and postprandial glucose level and it has been reported to be the major cause of mortality worldwide. There is an alarming projection of 471 million people with the disease by the year 2035. Diabetes is grouped into two forms; type 1, insulin dependent diabetes mellitus and type 2, non- insulin dependent diabetes mellitus. Type 2 is the major form accounting about 90% of cases worldwide. In type 2 diabetes mellitus (DM2), postprandial hyperglycemia is important in the development of the disease; Current treatment for Type 2 diabetes remains inadequate so prevention is preferable. The major strategy for the management of Type 2 diabetes is to decrease postprandial hyperglycemia. The α-glucosidase inhibitors, such as acarbose, have been used in the clinic to control blood glucose increase, especially postprandial, in DM2.Herbal medicine is predominantly available for the treatment of diabetes and the main advantages of the use of herbal drugs are effectiveness, safety, and acceptability. The mechanism of action of these medicinal plant of its products involve retarding the absorption of glucose by inhibiting the carbohydrate hydrolyzing enzymes, such as pancreatic amylase and α-glucosidase and through the inhibition of these enzymes, medicinal plants can effectively control the postprandial rise in blood glucose. Several medicinal plants have a high potential in inhibiting α-amylase enzyme activity.Annona muricata (A. muricata) is a tropical plant species belonging to family Annonaceae and known for its many ethnomedicinal uses. All parts of Annona are used in natural medicine in the tropics. It is considered to be a good source of natural antioxidants for various diseases. Traditionally, the leaves are used for headaches, insomnia, cystitis, liver problems, and diabetes, antitumor, anti-inflammatory. The health benefits of this plant have been attributed to their unique phytochemical composition.There is, however, a paucity of information that demonstrates the comparative α-amylase and α-glucosidase inhibitory properties of different extracts and fractions, of the various parts of the plant (fruit-pulp, leaf, stem-bark and root-bark) with relation to its anti-diabetic activity. Hence, the present study was carried out to investigate the comparative α-amylase and α-glucosidase inhibitory potentials of methanolic, ethyl acetate and dichloromethane extracts of the fruit-pulp, leaf, stem-bark and root-bark of Annona muricata and also to determine the possible modes and mechanisms of inhibition of these enzymes by these extracts. The justification for this research is the severe gastrointestinal side effects such as abdominal pain, flatulence and diarrhea that have been reported in the patients after the use of conventional drugs, so that the identification of natural interventions through the use of plants like Annona muricata, becomes beneficial due to their very minimal or absence of negative side effects.

Natural Products in the Treatment and Management of Diabetes

Natural Products in the Treatment and Management of Diabetes

Author: Mamdouh Moawad Ali

Publisher: LAP Lambert Academic Publishing

ISBN: 3659498432

Category:

Page: 60

View: 325

Diabetes mellitus is the most common metabolic disorder characterized by the presence of hyperglycemia due to defective insulin secretion, defective insulin action or both. Traditional Medicines derived from medicinal plants are used by about 60% of the world's population. We focus on herbal drugs and plants used in the treatment of diabetes. Diabetes is an important human ailment afflicting many from various walks of life in different countries. In Egypt it is proving to be a major health problem, especially in the urban areas. Though there are various approaches to reduce the ill effects of diabetes and its secondary complications, herbal formulations are preferred due to lesser side effects and low cost. A list of medicinal plants with proven antidiabetic and related beneficial effects and of herbal drugs used in treatment of diabetes is compiled. One of the etiologic factors implicated in the development of diabetes and its complications is the damage induced by free radicals and hence an antidiabetic compound with antioxidant properties would be more beneficial. Therefore information on antioxidant effects of these medicinal plants is also included.

Antioxidant-Antidiabetic Agents and Human Health

Antioxidant-Antidiabetic Agents and Human Health

Author: Oluwafemi Oguntibeju

Publisher: BoD – Books on Demand

ISBN: 9789535112150

Category: Medical

Page: 384

View: 524

The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.