Annotation This is a system- and disease-based approach to the aspects of gastrointestinal pathophysiology, essential for an understanding of clinical medicine. Bridging the gap between basic science and clinical medicine, this text provides students with a solid understanding of symptom identification and the underlying disease mechanism.
FROM THE PREFACE: The original purpose of the First Edition of Physiology of the Gastrointestinal Tract to collect in one set of volumes the most current and comprehensive knowledge in our field was also the driving force for the Fourth Edition. The explosion of information at the cellular level, made possible in part by the continued emergence of powerful molecular and cellular techniques, has resulted in a greater degree of revision than that of any other edition. The first section, now titled "Basic Cell Physiology and Growth of the Gl Tract" contains numerous new chapters on topics such as transcriptional regulation, signaling networks in development, apoptosis, and mechanisms in malignancies. Most of the chapters in this section were edited by Juanita L. Merchant. Section II has been renamed "Neural Gastroenterology and Motility" and has been expanded from seven chapters with rather classic titles to more than twenty chapters encompassing not only the movement of the various parts of the digestive tract but also cell physiology, neural regulation, stress, and the regulation of food intake. Almost all of the chapters were recruited and edited by Jackie D. Wood. The third section is entirely new and contains chapters on "Immunology and Inflammation" which were edited by Kim E. Barrett. The fourth section on the "Physiology of Secretion" consists of chapters with familiar titles, but with completely updated information to reflect the advances in our understanding of the cellular processes involved in secretion. The last section on "Digestion and Absorption" contains new chapters on the intestinal barrier, protein sorting and ion channels along with those focusing on the uptake of specific nutrients. These chapters were recruited and edited by Hamid M. Said and Fayez K. Ghishan. · Collected in one set - the most current and comprehensive coverage of gastrointestinal physiology · Information presented in a style that is both readable and understandable · Valuable to the specialized researcher, the clinical gastroenterologist, the teacher, and the student · Features an entirely new section on Immunology and Inflammation · Each section edited by the preeminent scientist in the field
Gain a foundational understanding of gastrointestinal physiology and how the GI system functions in health and disease. Gastrointestinal Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book. Helps you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, self-study questions, and a comprehensive exam. Keeps you current with recent advances in gastrointestinal physiology with coverage of the physiological significance of gastrointestinal peptides; the regulation of mucosal growth and cancer; details surrounding acid secretion and peptic ulcers; and more. Includes clear, 2-color diagrams that simplify complex concepts. Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations. Covers the regulation of pancreatic secretion and gallbladder contraction; the transport processes for the absorption of nutrients; facts about fat absorption; and the regulation of food intake. Complete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs. Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology Cloutier: Respiratory Physiology Koeppen & Stanton: Renal Physiology Pappano & Weir: Cardiovascular Physiology White, Harrison, & Mehlmann: Endocrine and Reproductive Physiology Hudnall: Hematology: A Pathophysiologic Approach
Gastrointestinal Physiology, a volume in the Mosby Physiology Monograph Series, explains the fundamentals of gastrointestinal physiology in a clear and concise manner. Ideal for your systems-based curriculum, this fully updated medical textbook provides you with a basic understanding of how the GI system functions in both health and disease. Stay current with clear, accurate, and up-to-the-minute coverage of the physiology of the gastrointestinal system focusing on the needs of the student. Bridge the gap between normal function and disease with gastrointestinal pathophysiology content throughout the book. Master the material more easily with learning objectives at the start of each chapter, overview boxes, key words and concepts, chapter summaries, and physiology review questions at the end of the book. Understand complex concepts by examining clear, 2-color diagrams. Apply what you've learned to real-life clinical situations with the aid of featured clinical cases with questions and explained answers. Consult the book online at Student Consult, where you can perform quick searches, add your own notes and bookmarks, and more! Stay abreast of the latest research and findings in physiology with coverage of the physiological significance of gastrointestinal peptides; the regulation of mucosal growth and cancer; details surrounding acid secretion and peptic ulcers; and more. Access new gastrointestinal information on the regulation of pancreatic secretion and gallbladder contraction; the transport processes for the absorption of nutrients; facts about fat absorption; and the regulation of food intake.
This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.
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This volume provides a practical hands on guide to gastrointestinal physiology. The book emphasizes an appreciation of basic physiological concepts and their application to novel clinical situations. It exposes the physician-in-training to fundamental principles that are useful in treating patients and lays the groundwork for more advanced study in the future. The authors present relevant cases which incorporate newer adult learning strategies in medical education. These cases provide a forum in which the student can apply acquired knowledge, skills and attitudes. Connections are made to reader’s life, whether in the classroom, on the wards or out and about town. Designed for medical students who are studying gastrointestinal physiology for the first time, Gastrointestinal Physiology: A Clinical Approach provides a superb review for upper level medical students and house officers. Nursing and allied health professions students will also find this text to be a useful guide. GI fellows and attending physicians in need of a concise review of fundamental GI physiology principles will also benefit from reading this book.
Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohn’s disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students. 2013 Highly Commended BMA Medical Book Award for Internal Medicine Discusses the multiple processes governing gastrointestinal function Each section edited by preeminent scientist in the field Updated, four-color illustrations
This collaboration of two physiologists and a gastroenterologist provides medical and graduate students, medical and surgical residents, and subspecialty fellows a comprehensive summary of digestive system physiology and addresses the pathophysiological processes that underlie some GI diseases. The textual approach proceeds by organ instead of the traditional organization followed by other GI textbooks. This approach lets the reader track the food bolus as it courses through the GI tract, learning on the way each organ's physiologic functions as the bolus directly or indirectly contacts it. The book is divided into three parts: 1) Chapters 1-3 include coverage of basic concepts that pertain to all (or most) organs of the digestive system, salivation, chewing, swallowing, and esophageal function, 2) Chapters 4-6 are focused on the major secretory organs (stomach, pancreas, liver) that assist in the assimilation of a meal, and 3) Chapters 7 and 8 address the motor, transport, and digestive functions of the small and large intestines. Each chapter includes its own pathophysiology and clinical correlation section that underscores the importance of the organ's normal function.
This collaboration of two physiologists and a gastroenterologist provides medical and graduate students, medical and surgical residents, and subspecialty fellows a comprehensive summary of digestive system physiology and addresses the pathophysiological processes that underlie some GI diseases. The textual approach proceeds by organ instead of the traditional organization followed by other GI textbooks. This approach lets the reader track the food bolus as it courses through the GI tract, learning on the way each organ's physiologic functions as the bolus directly or indirectly contacts it. The book is divided into three parts: (1) Chapters 1–3 include coverage of basic concepts that pertain to all (or most) organs of the digestive system, salivation, chewing, swallowing, and esophageal function, (2) Chapters 4–6 are focused on the major secretory organs (stomach, pancreas, liver) that assist in the assimilation of a meal, and (3) Chapters 7 and 8 address the motor, transport, and digestive functions of the small and large intestines. Each chapter includes its own pathophysiology and clinical correlation section that underscores the importance of the organ’s normal function.
